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For males during puberty, testosterone, along with gonadotropins released by the pituitary gland, stimulates spermatogenesis, along with the full sexual distinction of a human male from a human female, while women are acted upon by estrogens and progesterones to produce their sexual distinction from the human male.Sometimes gender scholars will use the phrase "hegemonic masculinity" to distinguish the most dominant form of masculinity from other variants.This is referred to as the XY sex-determination system and is typical of most mammals, but quite a few other sex-determination systems exist, including some that are non-genetic.The term primary sexual characteristics denotes the kind of gamete the gonad produces: the ovary produces egg cells in the female, and the testis produces sperm cells in the male.This difference in the relative amounts of these sex steroids is largely responsible for the physiological differences that distinguish men from women.During puberty, hormones which stimulate androgen production result in the development of secondary sexual characteristics, thus exhibiting greater differences between the sexes.The term manhood is used to describe the period in a human male's life after he has transitioned from boyhood, having passed through puberty, usually having attained male secondary sexual characteristics, and symbolises a male's coming of age. In English-speaking countries, many other words can also be used to mean an adult male such as guy, dude, buddy, bloke, fellow, chap and sometimes boy or lad.The term manhood is associated with masculinity and virility, which refer to male qualities and male gender roles.

*Manus in Indo-European mythology was the first man, see Mannus, Manu (Hinduism).

In the mid-twentieth century United States, for example, John Wayne might embody one form of masculinity, while Albert Einstein might be seen as masculine, but not in the same "hegemonic" fashion.

Anthropology has shown that masculinity itself has social status, just like wealth, race and social class.

Humans exhibit sexual dimorphism in many characteristics, many of which have no direct link to reproductive ability, although most of these characteristics do have a role in sexual attraction.

Most expressions of sexual dimorphism in humans are found in height, weight, and body structure, though there are always examples that do not follow the overall pattern.The male reproductive system's function is to produce semen which carries sperm and thus genetic information that can unite with an egg within a woman.

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